Let's Tear Down Dementia together! Over two days, scientists in the UK Dementia Research Insitute at King's College London along with other scientist

UK DRI at King's College London Opening Event: Tearing Down Dementia!

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Event UK DRI at King's College London Opening Event: Tearing Down Dementia!

Charity & Causes UK DRI at King's College London Opening Event: Tearing Down Dementia!

UK DRI at King's College London Opening Event: Tearing Down Dementia! London

UK DRI at King's College London Opening Event: Tearing Down Dementia! Charity & Causes London
UK DRI at King's College London Opening Event: Tearing Down Dementia! United Kingdom
  • London United Kingdom
  • Start: Feb 18 2019 12:45
  • Finish: Feb 19 2019 18:00
  • Time zone: Europe/London
This event is finished
Let's Tear Down Dementia together! Over two days, scientists in the UK Dementia Research Insitute at King's College London along with other scientists in the Maurice Wohl Clinical Neuroscience Institute will showcase new and cutting-edge research in the fight to end dementia. Talks will provide insight into the molecular mechanisms of neurogenerative diseases to better understand these diseases and pathways to cure them. Tear Down Dementia! Celebration On Monday, the day will close with a celebration of the UK DRI at King's and the Wohl Institute's researchers' commitment to ending dementia. This celebration will include a short talk on the importance of diversity in research along with an interactive session during which attendees will literally “tear down dementia.” About the UK Dementia Research Institute at King's College London “From bedside to bench to bedside with a cure” The UK DRI at Kings College London aims to identify the distinct and distinguishing features of different dementias using patient-derived ALS-, FTD- and AD data. This data will then be used to study etiologic mechanisms at the atomic, molecular, cellular and organism levels, to design early-stage diagnostics and to develop therapeutics for effective cure. Monday 18 February 2019 12:45 Registration 13:15 Welcome, Associate Director of UK Dementia Research Institute at King's College London Professor Chris Shaw 13:20 Official Opening, Executive Dean of Institute of Psychiatry, Psychology & Neuroscience Professor Ian Everall 13:30 Greetings, Director of UK Dementia Research Institute Professor Bart de Stooper 13:35 Vision of the UK DRI, Director of UK Dementia Research Instiute, Operations, Dr Adrian Ivinson Session 1- RNA Binding Proteins & RNAs in Neurodegeneration 13:45 Professor Chris Shaw, ARPP21 is an ALS Gene: thinking outside the nuclear box 14:10 Priv-Doz, Dr Marc-David Ruepp, FUS-RNA interactions in health and disease 14:35 Dr Jemeen Sreedharan, MRI reveals cerebellar and frontal cortical deficits in the TDP-43(Q331K) knock-in mouse model of ALS-FTD 15:00 Dr Elsa Zacco, Natural RNA-protein interactions for preventing aberrant aggregation: the case of TDP-43 15:15 Break/Tea/Coffee Session 2- Glia in Neurodegeneration 15:45 Professor Dr Christian Haass, Keynote, TREM2 function and dysfunction in neurodegenerative diseases 16:00 Professor Lawrence Rajendran, TBA 16:15 Professor Marios Politis, PET imaging of neurodegeneration 16:30 Dr Maria Jimenez Sanchez, Astrocyte-secreted chaperones and their role in astrocyte-neuron communication 16:45 Professor Josef Priller, University of Edinburgh, TBA 17:00 Dr Walther Haenseler, University of Zurich, Modelling neurodegenerative diseases with human pluripotent stem cell derived microglia 17:30 Tear Down Dementia! Celebration Wohl Cafe Tuesday 19 February 2019 09:00 Registration Session 3- Post-tranlsational Modifications 09:30 Professor Sir Christopher Dobson, Keynote, The kinetics and mechanisms of protein aggregation 10:00 Professor Annalisa Pastore, Post-translational modifications in neurodegeneraiorn 10:20 Dr Francesco Aprile, University of Cambridge, Targeting Alzheimer's associated amyloid oligomers using antibodies 10:40 Dr Manuel Müller, Chemical synthesis of post-translationally modified proteins 11:00 Break/Tea/Coffee Session 4- Advanced Imaging in Neurodegeneration 11:30 Dr Sarah Mizielinska, Dysfunctional nucleocytoplasmic transport in FTD/ALS - a direct role for the nuclear pore? 11:50 Dr Caroline Vance, FUS function and dysfunction at the neuromuscular junction 12:15 Dr Alessio Vagnoni, Probing the intracellular dynamics of ageing neurons in Drosophila and beyond 12:40 Dr Kate Sellers, Imaging the nanoscopic organisation and dynamics of synapses in AD 13:00 Lunch & poster session Session 5- Synapse and disease 14:15 Dr Morgan Sheng, Keynote, Mechanisms of synapse loss in Alzheimer’s disease and tauopathy 14:50 Professor Kei Cho, Synapse weakening: Phathophysiology of Alzheimer’s disease 15:10 Professor Peter Giese, Do deficits in synaptic protein synthesis underlie pathology and memory loss in Alzheimer's disease? 15:30 Professor Juan Burrone, Plasticity of axo-axonic synapses at the axon initial segment 15:45 Professor Chris Shaw, Closing Remarks

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